Urinary pH modifiers are pharmaceutical agents used to alter the pH of urine to prevent or manage specific urological conditions. Alkalinizing agents (e.g., sodium bicarbonate, potassium citrate, sodium citrate, tromethamine) raise urine pH to solubilize uric acid and cystine stones, reduce uric acid crystal formation in gout or uric acid nephrolithiasis, and enhance excretion of certain drugs...